Neuroimaging may shed light on how Alzheimer’s disease develops
Alzheimer's disease (AD) research indicates that accumulation of amyloid-beta (Aβ) protein plaques in the brain is central to the development of AD.
viaNeuroimaging may shed light on how Alzheimer’s disease develops.
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Soluble amyloid-beta precursor protein (sAPP) plays an important role in the epidermal melanin-unit as an epidermal growth factor stimulating melanin production in melanocytes and the transfer to keratinocytes. In the end – AD also a daylight deficiency disease?
Source:
Quast, Thomas, Sven Wehner, Gregor Kirfel, Klaus Jaeger, Michele De Luca, and Volker Herzog. „Sapp As a Regulator of Dendrite Motility and Melanin Release in Epidermal Melanocytes and Melanoma Cells.“ The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17, no. 12 (2003): doi:10.1096/fj.02-1059fje.
Schmitz, A, R Tikkanen, G Kirfel, and V Herzog. „The Biological Role of the Alzheimer Amyloid Precursor Protein in Epithelial Cells.“ Histochemistry and cell biology 117, no. 2 (2002): doi:10.1007/s00418-001-0351-5.